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PT-141
Cyclic melanocortin-receptor agonist peptide (bremelanotide) for receptor pharmacology research.
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Bacteriostatic Water
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- Supplied as
- Lyophilized powder in a sealed vial. Bacteriostatic water sold separately.
- Storage
- 2–8 °C refrigerated, or −20 °C for long-term storage. Keep refrigerated after reconstitution.
- Delivery
- Dispatched the same business day; shipping calculated at checkout, free on orders of $199.00 or more. US addresses only.
— Product Overview
Description
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide and analog of alpha-melanocyte-stimulating hormone (α-MSH), developed from the melanotan peptide family. It acts as a melanocortin-receptor agonist with notable activity at MC3R and MC4R, and its cyclic lactam structure gives it greater metabolic stability than linear MSH analogs.
Emerging from melanocortin structure-activity research at the University of Arizona, PT-141 has one of the most thoroughly documented receptor-binding and pharmacokinetic profiles of any research peptide, studied across cell, rodent, and primate models for central melanocortin-pathway activity.
Supplied as a lyophilized powder for laboratory research use only. Not for human consumption.
Research & comparisons
PT-141 (Bremelanotide): Research Overview, Mechanism and Handling
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Research article · Sep 2026
PT-141 (Bremelanotide) vs Melanotan II
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Frequently Asked Questions
What is PT-141?
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-MSH that acts as a melanocortin-receptor agonist, with notable activity at MC3R and MC4R.
What is PT-141 studied for in research?
It is studied in cell and animal models for melanocortin-receptor pharmacology and central nervous system signaling, distinct from peripheral vascular-acting compounds.
How is PT-141 different from Melanotan II?
PT-141 is structurally derived from the melanotan peptide family but is a cyclic analog with a different receptor-activity and stability profile.
How is PT-141 supplied?
As a lyophilized powder for laboratory research use only. It is not for human consumption.
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PT-141